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Moreover, the activity of ADH was much higher than the activity of ALDH (ratio 55:1) which is not enough to prevent acetaldehyde accumulation [44]

Uric acid has been shown to prevent glutamate-induced cell death in vitro and to inhibit ROS and RNS to reduce infarct size and improve prognosis in rodents after transient or permanent cerebral ischemia (Squadrito et al., 2000