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Each form of B12 works along different biological pathways within the body

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This can be prevented by supplementing with L-glutamine, which maintains the integrity of the intestinal barrier and reduces the incidence of gut-derived infections.[108] Glutamine appears to have the most benefit when inflammation is present despite the depletion of nutritional stores.[109] It reduces inflammatory cytokine release within the bowel wall[110] and increases heat shock protein, which protects enterocytes from injury