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Cystine uptake assay For in vivo detection of tumor cell cystine uptake, 13 C 6 - 15 N 2 -labeled cystine was administered to mice via intraperitoneal (i.p.) injection

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She completed her General Surgery residency at the University of Pittsburgh Medical Center (UPMC) where she served as Administrative Chief Resident, then remained at UPMC to complete a fellowship in Complex Surgical Oncology, during which she again served as Administrative Chief Fellow.[1] Following the completion of her fellowship training, Dr

In tumor cells, MYC-driven glutamine metabolism promotes tumor growth, drug resistance and immune escape [48], whereas MYC-regulated glutamine metabolism in immune cells supports the activation, proliferation and cytokine secretion of effector T cells and NK cells and enhances the immune response and other immune functions [49]