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In PD, mutations in GBA, ATP13A2, and PARK9 impair lysosomal function, leading to -synuclein accumulation and cellular toxicity (Behl et al., 2022

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doi: 10.1523/JNEUROSCI.2209-07.2007, Summary Keywords central nervous system, degenerative compressive myelopathy, microglia/macrophage, neuroinflammation, neuropathic pain, ossification of posterior longitudinal ligament, spinal cord, spinal cord injury Citation Kubota A, Nakajima H, Honjoh K, Watanabe S, Takahashi A and Matsumine A (2026) Differential microglial dynamics and neuroinflammation underlying neuropathic pain in the central nervous system: comparative insights from spinal cord injury and compressive myelopathy models