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Description

Xct contributes to colorectal cancer tumorigenesis through upregulation of the melk oncogene and activation of the Akt/Mtor cascade

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Importantly, LNPs-RNA formulations can potentially overcome non-druggable targets to treat diseases that cannot be addressed with current medicines, such as neurodegenerative disorders and genetic diseases

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This explains the lack of tolerance and dependence liability observed in animal studies

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Shishko PI, Dreval AV, Abugova IA, Zajarny IU, Goncharov VC

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Tinker, A

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