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Lim S, Janzer A, Becker A, Zimmer A, Schle R, Buettner R, et al

Tregs suppress autoimmune activity

It is therefore assumed that transcription from gdhA P2 serves to enhance gdhA expression when the concentration of -ketoglutarate is low, as during invasive disease, both to enhance the activity of the TCA cycle in the catabolic reaction, and to provide L-glutamate for glutathione biosynthesis in the anabolic reaction