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Auswahl des passenden Protokolls Wenn eine Infusionstherapie sinnvoll erscheint, wird mglichst gezielt entschieden: welches therapeutische Ziel verfolgt wird welche Substanz oder Kombination plausibel ist in welcher Dosis und Frequenz sie sinnvoll sein kann wie die Infusion in das Gesamtkonzept passt 3

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In acute gout, MSU crystals, liberated from tissue deposits by remodeling effects or microtrauma, stimulate inflammatory cascades that involve complement activation and assembly of the C5b-9 membrane attack complex, and release of multiple inflammatory cytokines, including IL-1 and the chemokines IL-8 (CXCL8) and GRO- (CXCL1)

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The attainment of this effect was mediated through the enhancement of antioxidant enzyme activity, thereby restoring the visibly elevated biochemical levels caused by the injury to the normal range (Lisina et al., 2011)

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