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Description

Yamkate P, Gold RM, Twedt DC, Suchodolski JS, Steiner JM, Lidbury JA

The GHRH receptor pathway CJC-1295 binds to GHRH receptors on somatotroph cells in the anterior pituitary gland

Mechanistically, treatment with ganoderic acid A (Zhang et al., 2025), DGA (Yue et al., 2024), and pachymic acid (Li et al., 2022) improved intestinal dysfunction, macrophage pyroptosis, and pancreatic fibrosis in AP by repressing NLRP3 inflammasome activation