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This work was funded by: TS (Baylor College of Medicine, U01-AI24290, P01-AI152999, NINR R01-NR013497, and NIDDK P30-DK56338), SJW (NIDDK 1R41DK119052-01 and NIA P30-AG024832 [PI: E

For the beta diversity analyses, an analysis of similarities (ANOSIM) was performed on each of the distance/dissimilarity matrices to establish whether observed clustering by treatment group was statistically significant

B12 is delivered through an IV infusion by inserting a small catheter into a vein, allowing a saline-based solution containing vitamin B12 to flow directly into the bloodstream