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Unreacted O 2 .- moves through voltage-dependent anion channels (VDAC) into the cytosol, where some is also enzymatically converted to H 2 O 2

Screen-detected HCC was defined as abnormal surveillance-intent abdominal imaging or alpha-fetoprotein within 6 months before diagnosis

Studies on gut microbiota transplantation in animals confirmed that dysbiosis may increase thyroid autoimmunity susceptibility [179]

However, rutin is capable of creating adducts with histidine residues in the active site of tyrosinase, which leads to tyrosinase inhibition and stops the production of melanin [74]

Medical physics 50(1):323-329, 2023