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It was originally investigated for the treatment of Alzheimers disease and Parkinsons disease, and was subsequently dropped from development for these applications after early trial results showed limited efficacy for treatment of these diseases

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Activity changes: Some experience fatigue or reduced energy on GLP-1s, leading to less physical activity and resistance training that would otherwise preserve muscle

Glycine as an OTC supplement If you are concerned about muscle loss due to rapid weight loss with semaglutide, you may be able to use glycine supplementation as a separate, over-the-counter (OTC) product after consulting with your doctor

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