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Force field optimization guided by small molecule crystal lattice data enables consistent sub-angstrom protein-ligand docking

Specifically, the relative abundance of Desulfobacterota doubled in the anterior region, while the levels of Firmicutes increased and Proteobacteria, Actinobacteriota, and Campylobacterota were reduced in the posterior region when supplementing the diet with bile salts (Ruiz et al., 2023)