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Similarly, network pharmacology uncovered the molecular basis by which the natural compound 2-hydroxychalcone ameliorates copper sulfate-induced inflammation in zebrafish (Shen et al., 2025), and clarified how Moutan Cortex ( Paeonia suffruticosa ) exerts its anti-inflammatory and blood-activating effects via modulation of the coagulationinflammation cascadea mechanism validated across cellular, rat, and zebrafish models

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Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Satoh N, Kyotani K, Mizowaki T, Imahori T, Ejima Y, Masui K, Gini B, Yang H, Hosoda K, Sasaki R, Mischel PS, Kohmura E

Jia JN, Yin XX, Li Q, Guan QW, Yang N, Chen KN

Point to remember: Its important to remember that these benefits are most effective when combined with a diligent skincare routine and a healthy lifestyle