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Enrofloxacin has been administered to dogs at a daily dosage rate of 10 mg/kg concurrently with a wide variety of other health products including anthelmintics (praziquantel febantel) insecticides (pyrethrins) heartworm preventatives (diethylcarbamazine) and other antibiotics (ampicillin gentamicin sulfate penicillin)

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Furthermore, while our work highlighted transcriptional outcomes and intracellular signaling pathways, we did not investigate epigenetic modifications, which are key regulators of developmental transitions and events and could underly the development deficits observed here