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If insufficient folic acid is not available uracil is substituted for thymidine in DNA, which leads to DNA strand breakage

Liver transplantation can be taken into consideration if necessary

All participants experienced at least one psychotic episode and were able to speak and understand English

After neutralization with 0.5 M phosphate buffer (7.5), 0.1 mL of the supernatant was added to a reaction mixture containing 0.2 mM NADPH, 100 mM phosphate buffer (pH 7.5), 5 mM EDTA, and 0.6 mM 5,5dithio-bis (2-nitrobenzoic acid)

Rich lipofuscin granules have been observed in lymphocytes from aged mice, and it is known that lipofuscin may act as a danger signal, stimulating the release of pro-inflammatory chemokines and cytokines and activating macrophages, thereby leading to a chronic oxidative-inflammatory process 52