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Laboratory protocols typically utilize dosing ranges that maintain safety margins while achieving research objectives, with careful attention to the compound's effects on hypothalamic-pituitary axis function

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J Mol Med 77:495504 Hisano S, Daikoku S, Yanaihara N, Shibasaki T (1986) Intragranular colocalization of CRF and Met-Enk-8 in nerve terminals in the rat median eminence

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