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Description

NMR 66 , 111124 (2016)

While B12 is water soluble, excess amounts can still be toxic

Similar to IKEMA, the primary outcome in CANDOR was PFS

While not every person benefits, and while nausea often resolves on its own after 2-3 weeks on a stable dose, any intervention that improves tolerability increases the likelihood that users remain on treatment long enough to achieve meaningful results