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1a, under gastric acid conditions, PtCo@G exhibited an intrinsic oxidase-like property to catalyze superoxide radical (O 2 ) generation, as one of the highly toxic ROS, to attack the bacterial membrane and cause cytoplasmic leakage, resulting in bacterial death 24

Many different types of pathogens, including bacteria, fungi, protozoa, viruses, and parasites may cause infectious damage to the CNS

B12 deficiency can have serious consequences if left untreated