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Comparing the former version of these documents and the 2026 updated ones, the major changes are: Further examples or clarifications have been added to the following substance classes to help athletes and their entourage better identify prohibited substances: S1

GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine

Because it originates in gastric juice, its natural target tissues are the stomach, small intestine, and colon

As the educators at the International Dermal Institute put it in their guide, Copper Peptides in Skin Care: Hype or Helpful

doi: 10.1186/s12896-022-00771-5