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Focal Adhesion Kinase (FAK) Pathway: The activation of FAK under laboratory conditions suggests that the peptide assists in reorganising the cellular cytoskeleton, allowing cells to move more efficiently across the testing substrate

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The protective role of PERK during hypoxic stress has been shown using mouse embryonic fibroblasts (MEFs) isolated from PERK-null mice, where PERK-deficient MEFs are more sensitive to hypoxic stress than their wildtype counterparts 40,41

A., Isah, M

Table 3 summarizes the current stage of each biomarker category and key barriers to its clinical implementation