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Through a novel process set up for this project, we generated postbiotics by letting the proprietary strain Lactobacillus paracasei LMG-S-26420 ferment for 72 h under anaerobic conditions in the presence of a freeze-dried botanical hydroalcoholic extract of garlic ( Allium sativum )

Smeland OB, Meisingset TW, Borges K, Sonnewald U

Nusinersen-mediated SMN upregulation modulates GABAergic signalling and protein expression in SMA cortical cultures To further evaluate the role of SMN deficiency in the dysregulation of GABAergic signalling at the neuronal level, we investigated whether restoring SMN levels could modulate the expression of genes and proteins involved in GABA synthesis and transport in cortical cultures

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Children receiving CRWP showed a significant increase in glutathione levels and selective improvements in adaptive behavior and socialization domains ( Glutathione is able to improve the antioxidative system decreasing the oxidative damage and the neuroinflammation caused to the neurons (Ghanizadeh et al., 2012)