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Given that these compounds dont work in vivo , Ive debated whether their MoA is interesting or important enough to spend time thinking about, but Ive tended to come down on the side that this line of inquiry could yield some insights into prion biology and potential points for therapeutic intervention

Common side effects with creatine include water retention, dehydration, muscle cramps, weight gain, digestive issues, and kidney stress

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Regulation of erythropoietin production is related to proximal tubular function

Studies have shown it can reset aging genes toward a more youthful expression pattern, a finding that has genuinely excited researchers in the longevity space