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Men should contact their GP or trial clinician promptly if they experience severe abdominal pain, persistent vomiting, signs of dehydration, or any unexpected symptoms

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In this study, authors demonstrate that MEM was effective only on high molecular-weight oligomers and concluded that the limited clinical efficacy of MEM in AD could be explained by this selectivity [51]

However, clinical studies show no significant benefit in functional stability, patient reported outcomes or retear rates

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