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The subsequent dampening of wound neutrophil-derived elastase levels prevents excessive degradation of ECM proteins

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K ATP is closed in response to high glucose, leading to depolarization of the plasma membrane, which triggers secretion of GLP-1-containing vesicles

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Theoretically, the most promising formulations, which exceed the limitations imposed by the physico-chemical characteristics of cannabinoids, mentioned above are those that allow their administration on the skin [154]