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Future research should focus on understanding how the regulation of this mixed cell death affects cardiac energy metabolism

Disclosure of interest: Laia Carballo-Perich: nothing to disclose

Abbreviations 5-HT3: 5-Hydroxytryptamine type 3 (Serotonin) receptor + 1 ACOG: American College of Obstetricians and Gynecologists + 1 CNS: Central Nervous System CPM: Cycles Per Minute D2: Dopamine receptor D2 + 1 FDA: Food and Drug Administration GDF15: Growth Differentiation Factor 15 + 3 GERD: Gastroesophageal Reflux Disease H1: Histamine type 1 receptor + 1 HCG (hCG): Human Chorionic Gonadotropin + 1 HG: Hyperemesis Gravidarum + 1 IV: Intravenous + 3 NG: Nasogastric (tube) + 3 NJ: Nasojejunal (tube) + 2 NVP: Nausea and Vomiting of Pregnancy + 1 PICC: Peripherally Inserted Central Catheter PTSD: Post-Traumatic Stress Disorder PUQE: Pregnancy-Unique Quantification of Emesis (score) + 1 RCOG: Royal College of Obstetricians and Gynaecologists RCT: Randomized Controlled Trial + 1 RYR2: Ryanodine Receptor 2 + 3 SGA: Short (Small) for Gestational Age TPN: Total Parenteral Nutrition + 1 TSH: Thyroid-Stimulating Hormone References Abramowitz A, Miller ES, Wisner KL (2017) Treatment options for hyperemesis gravidarum

10.1007/s13277-014-2778-z 7 AggarwalB

Hypothetically, if we can reduce inflammation, we might also reduce 5-alpha reductase activity (and thereby DHT levels)