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Results Mice treated with LPS exhibited mitochondrial dysfunction, oxidative stress, an inflammatory response, neural cell apoptosis, and loss of dendritic spines in the hippocampus, leading to impaired hippocampus-related learning and memory performance in the MWM and contextual fear conditioning test

METHODS: A decision tree model was developed using a 68-week time window with consideration of serious adverse events and treatment discontinuation from a US payers perspective

USA 107 , 1183511840 (2010)

Preclinical assessment on neuronal regeneration in the injury-related microenvironment of graphene-based scaffolds