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UMO-2018/30/E/ST4/00481 and by the Warsaw University of Technology under the program Excellence Initiative, Research University (IDUB), BIOTECHMED-1 project No

NRF2 then dimerizes with members of the sMaf proteins through its bZIP domains and binds to the ARE sequences, which are regulatory enhancers, within gene promoters [156, 161]

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Pharmacological inhibition of JNK prevented 4-HNE-induced LC3-II formation, suggesting that 4-HNE triggered autophagic responses could be partly attributed to ER stress [155]