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Mature cDCs suppress tumor angiogenesis by secreting anti-angiogenic cytokines, namely, IL-12 and IL-18, and angiostatic chemokines, including CXCL9, CXCL10, and CCL21 62,63,64

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Our results revealed that altered metabolomic profiles might contribute to the pathogenesis and course of MS disease by modulating immuno-inflammatory responses in the peripheral system, which is essential for eliciting autoimmune responses in the central nervous system, thus resulting in the progression of MS

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