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A blood count may show an increased white cell count and ESR, but it is often normal

Absolute deficiency or malfunction of CBS disrupts this pathway, leading to elevated blood and urine levels of homocysteine and methionine, and reduced cysteine levels (18)

J Clin Oncol 2007

Biochem Pharmacol 119:7684 Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians