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They were initially defined as secretory GPX, but later studies have shown that both enzymes are localized to the endoplasmic reticulum and are necessary enzymes involved in the oxidative folding of endoplasmic reticulum proteins (Figure 8)

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If you experience any of the following side effects after taking folic acid or a supplement like ferrous ascorbate and folic acid tablets, be sure to contact your doctor right away: Fever Feeling generally weak or uncomfortable Shortness of breath Feeling itchy, or experiencing a skin rash or reddened skin Difficulty breathing Wheezing A tight feeling in your chest Harvard Health: "Iron and Your Health" Johns Hopkins Medicine: "Folate-Deficiency Anemia" National Institutes of Health: Office of Dietary Supplements: "Iron" Mayo Clinic: "Folate (Folic Acid)" University of Rochester Medical Center: "What Are Red Blood Cells?" Amway: "Nutrilite Iron Folic" Vitamin Shoppe: "MegaFood: Blood Builder With Whole Food Iron & Organic Beet Root: Supplement Facts" University of Michigan: Rogel Cancer Center: "Why Is Iron Important in My Diet?" Mayo Clinic: "Folic Acid (Oral Route, Injection Route)"

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