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Excess free radical production can be triggered by a variety of external factors, each of which effectively disrupts the oxidant-antioxidant balance in the body

Sources NIH: Mitophagy Promotes Hair Regeneration by Activating Glutathione Metabolism NIH: Glutathione and its antiaging and antimelanogenic effects MedicalNewsToday: What are the benefits of glutathione

As a paradigm, Wu and co-workers integrated Au nanoclusters (Au NCs) with histidine to accomplish GSH exhaustive-prompted RT, denoted as Au NCs@His (Figure 7A) (Zhang et al., 2018)

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The intravenous administration of liposomes loaded with PDE3B siRNA was observed to promote the macrophage anti-inflammatory program, reduce the inflammatory response and synoviocyte infiltration, and attenuate bone and cartilage erosion in CIA mice