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Statistical analyses were conducted using the GraphPad Prism 9.0 software suite

In vivo study: After treated with LW231 for 42 days in the AAV-HBV mice, the mean declines in HBV DNA was 0.2, 2.2 and 2.3 logs, in HBsAg was 0.3, 0.8, 0.5 logs, in HBeAg was 0.08, 1.1, 0.7 logs comparison to pretreatment levels in mice dosed with 50, 100 and 200 mg/kg LW231, respectively

Phyllanthus niruri Phytochemical characteristics of Phyllanthus niruri particularly hydroalcoholic extracts of the leaves discipline flavonoids which contain quercitin, gallic acid, and rutin these compounds have been established to have pharmaceutical value

Brady OA, Meng P, Zheng Y, Mao Y, Hu F

These analgesic properties position DSIP as valuable research compound for developing non-opioid pain management strategies, understanding the relationship between sleep and pain processing, and investigating peptide-based approaches to chronic pain treatment