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[15] [13] Other notable adverse effects include: Hypoglycemia : Low risk when used as monotherapy, but increased when combined with insulin or sulfonylureas Injection site reactions : Erythema, pruritus, or discomfort in approximately 2% to 4% of patients Fatigue and dizziness : Reported in 5% to 8% of participants Increased heart rate : Mean increases of 2 to 4 beats per minute observed [1] [2] Serious adverse events were uncommon but included acute pancreatitis (approximately 0.2% incidence), gallbladder disease including cholecystitis and cholelithiasis (0.6% in diabetes trials and up to 2.5% in weight management trials, associated with rapid weight loss), and acute kidney injury, typically in the context of severe dehydration from gastrointestinal symptoms

The good news is that if caught early, the conventional treatment typically uses prescription eyedrops to lower the IOP

In HEK293 cells, CHCHD2 knockdown was accompanied by decreased expression of superoxide dismutase 2 and loss of glutathione peroxidase expression [15]

This isnt just about optimising workflows or doing things faster, but rather about changing the way we operate to do things in a more integrated, consistent, and data-driven manner

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