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Nevertheless, it can be hypothesized, that the whole PBMC population was experiencing metabolic stress by LPS addition in the present study, which may be the reason for decreased OCR

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Future studies need to include standardised techniques and analyses when doing further research into the virome as it is particularly understudied in ME/CFS ( External stressors like stressful or traumatic incidents, acute infection, and toxic stressors may result in widespread and chronic systemic and even neuroinflammation, driven by a variety of inflammatory molecules in circulation

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