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Peptides can potentially improve symptoms, strengthen the skin barrier, and reduce inflammation, but they do not alter the underlying genetic predisposition

Galli SJ, Maurer M, Lantz CS

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Adiponectin, the most abundant adipokine in circulation [220], exerts its biological effects via two primary receptors (AdipoR1 and AdipoR2) [221], these receptors exhibit differential expression patterns across hepatic cell populations, including hepatocytes, HSCs, and KCs, mediating beneficial effects such as anti-inflammatory responses and anti-fibrotic actions [222, 223]