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J Clin Invest 2016;126:4361-71.ArticlePubMedPMC 109

The musclebrain metabolic axis refers to the bidirectional communication network through which skeletal muscle and the central nervous system coordinate energy metabolism, signaling, and functional adaptation

Cells were then transfected with 1 g mRFP-GFP-LC3 plasmid in 3 L of PEI (1 mg/mL)

30 KRAS G12D inactivation, in contrast, downregulated global protein glycosylation, suggesting that KRAS G12D -mediated glucose utilization via HBP is essential for O -GlcNAcylation