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The discovery of histone lactylation further reveals lactates capacity to directly reshape macrophage gene expression

Seizures may be treated efficiently by life-long supplementation with pyridoxine or its biologically active form, pyridoxal phosphate, but even so patients may become intellectually disabled, for which there currently is no effective treatment

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According to the treatment method, it can be divided into Chinese medicine treatment and western medicine treatment

A plaques result from the abnormal cleavage of amyloid precursor protein (APP) by betasecretase (BACE1) and gammasecretase, leading to the aggregation of A peptides, particularly A42, which is highly toxic to neurons (Hardy and Selkoe 2002)