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Shikonin (SHK), a natural compound isolated from Lithospermum erythrorhizon roots, exhibits diverse bioactivities, including antioxidant, anti-inflammatory, and antitumor effects, and functions as a proteasome inhibitor and necroptosis inducer (Yan et al., 2023)

Comparative evaluation of solvent systems for improving the solubility and stability of SLU-PP-332 in preclinical formulations

By binding intestinal BAs and promoting their excretion, BASs reduce the BA pool returning to the liver, potentially decreasing BA-induced hepatotoxicity and altering systemic BA signals (134)

For instance, glucoproteins like glucose transporters can be exploited to deliver therapeutics that mimic glucose

Another example is the loading of carboplatin (CTX) into CTX-LPNs, which are formed by the self-assembly of polyblock copolymers