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Rotenone also increases the expression of the autophagy-related proteins LC3-II and BECLIN1, as well as autophagy substrates such as -syn and p62 [120]

In CD patients and chemically induced murine colitis models, stanniocalcin-1 (STC1) stimulates parthanatos via the STC1-PARP1-JNK pathway and the JAK pathway [89]