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Thus, ATP and ATP-mediated transporters and signaling pathways are thought to play influential roles in the development of drug resistance

Additionally, modulating signaling pathways, such as AKT pathways, influence parthanatos by altering intracellular ROS levels in colon cancer cells [159]

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Long-Term Safety and Biocompatibility Studies: A deeper understanding of the long-term safety and biological fate of AI-designed nanomaterials is required