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SKU: 87523377340
Price: 29.12 USD
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HisD (histidinol dehydrogenase) has been identified as a potential target for novel anti-TB drugs due to its essential role in histidine synthesis ( MTB proliferation ( MTB ( MTB significantly hampers MTB growth ( MTB growth ( We focused first on evaluating the protective efficacy of these three antigens, and planned to perform detailed immunogenicity evaluation on any antigens found to be protective, given the lack of defined and validated immune correlates of protection for TB ( MTB challenge ( ex vivo MGIA provides an unbiased tool for high-throughput down-selection of promising protective antigens ( Both metE-DNA and metE-AS01 vaccine candidates induced a Th1-skewed phenotype, characterized by the expression of IFN, TNF, and IL-2