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A small portion of glutamate is oxidatively metabolized, thus making synthesis of glutamate necessary to maintain adequate glutamate levels [24]

J Musculoskelet Neuronal Interact

Therefore, it is conceivable that different cell types, such as hepatocytes and beta cells, have distinct needs for oxidation versus reduction, dependent not only on the types of proteins that a given cell type has to secrete, but also on cellular conditions such as nutrient fluxes that impact the relative composition of the secretome at any given time

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