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However, to date, there are no FDA-approved treatments available for all patients with ALD, especially those who will ultimately develop one of the ALD phenotypes in the later decades of life

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PMID: 7319296

Environmental remediation technologies show promise but require substantial infrastructure investments and long-term maintenance commitments that may not be feasible in all regions

O 2 further undergoes dismutation reaction catalyzed by SOD or O 2 can be reduced by PQH 2 (see above), to produce H 2 O 2 , which in turn is reduced by Asc with the involvement of ascorbate peroxidase (APX), generating H 2 O and monodehydroascorbate radical (MDHA) (Figure 5)