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Commonly suggested biomedical hypotheses to explain PAIS (such as in long COVID/PASC, ME/CFS) are chronic stimulation of the immune system by a persistent infection or persistent unviable pathogen structures

[DOI] [PubMed] [Google Scholar] 11.Giustarini D, Dalle-Donne I, Milzani A, Rossi R

7A and 9A, respectively

This dysregulation is especially problematic in the case of critical illness when a lack of Se might worsen NTIS because thyroid hormones are not regulated adequately to meet the needs of metabolism [52]