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Current studies still commonly face limitations in causal inference and model systems: most findings are derived from in vitro induction systems or single animal models, making it difficult to simultaneously resolve the coordinated influence of tissue substrate availability, intercellular metabolic division of labor, and local cytokine networks on metabolic pathways

The use of ORAI1 inhibitors, such as CM4620, GSK-7975A and CM_128, has been suggested as a therapeutic approach, effectively reducing cytosolic Ca 2+ overload in pancreatic cells and mitigating the inflammatory response associated with pancreatitis (204, 205)

Enzyme-mediated tumor starvation and phototherapy enhance mild-temperature photothermal therapy

5 End nicotinamide adenine dinucleotide cap in human cells promotes RNA decay through DXO-mediated deNADding

Atmos Environ 97:121129