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"The data and hypothesis are very intriguing, but much additional investigation is required to determine if this is a real cause-and-effect phenomenon," said Josh Miller, a professor of nutritional sciences at Rutgers University who was not involved with the study

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In view of the microvascular and macrovascular benefits and long-term legacy effects of early, intensive HbA1c control, it would seem logical to introduce a highly effective agent such as tirzepatide early in the T2D treatment pathway

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Rahul Bhargava Anusha S

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Strinic, Z

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University of California San Francisco

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