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Additionally, these substances depleted ATP levels, impaired mitochondrial function, reduced cell proliferation, and induced autophagy, necrosis, and apoptosis 50

Genetic studies reveal the role of the endocrine and metabolic systems in aging

Metabolomics profiling of mouse plasma, MRS medium, and bacterial supernatants Ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) analysis Four volumes of 80% methanol in water were added to 20 L of mouse plasma, bacterial culture supernatants, or MRS media