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Perhaps most important, given that CVD accrues as a function of advancing age, is evidence from rodent models that exercise induced cardioprotection is effective against ischemic insults in both young and old animals (Starnes et al., 2003

Results from the application may be more localized and gradual compared to supplementation

Statements Author contributions MoA: Investigation, Validation, Visualization, Writing original draft, Writing review and editing

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()-Kavain inhibits the veratridine- and KCl-induced increase in intracellular Ca2+ and glutamate-release of rat cerebrocortical synaptosomes