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It has been reported that ROS stimulated the oxidation of thioredoxin and its dissociation from ASK1 (Matsukawa et al

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doi: 10.4137/IJTR.S26862 197 BaevAYVinokurovAYNovikovaINDreminVVPotapovaEVAbramovAY

PLOS ONE 11 , e0146931 (2016)