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KPV directly addresses the NF-kB dysregulation and cytokine overproduction that define psoriasis at the molecular level

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The REMS was set to go into effect on 8 August, but the agency said it wants to allow more time to test the iPLEDGE REMS system updates, minimize technical issues for iPLEDGE REMS platform users, and ensure patients continue to have access to isotretinoin treatment